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$27.9 million from NIH to support Baylor’s Knockout Mouse Project
Articles / Award / Genetics

$27.9 million from NIH to support Baylor’s Knockout Mouse Project

Nearly $28 million has been awarded to Baylor College of Medicine’s Knockout Mouse Project led by Dr. Arthur Beaudet, professor of molecular and human genetics, and Dr. Mary Dickinson, professor of molecular physiology and biophysics. The grant, to be used over 5 years, was awarded by the National Institutes of Health as a renewal of … Continue reading

Variations in gene ATAD3A can result in distinct neurological syndromes
Articles / Human genetics

Variations in gene ATAD3A can result in distinct neurological syndromes

Research has revealed that a group of rare neurological syndromes for which there was no cause can be the result of variations in the gene ATAD3A. The study, which appears in The American Journal of Human Genetics, shows that certain human variants of ATAD3A are associated with a lower number of mitochondria while the gene equivalents in the … Continue reading

A new mechanism to explain benign prostatic hyperplasia
Articles / inflammation / prostate

A new mechanism to explain benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate, affects about half the men between 51 and 60 years of age, and nine out of 10 men older than 80. How BPH happens, however, is still open for debate. “Scientists have considered that inflammation can cause BPH. But how inflammation initiates in human prostate … Continue reading

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men
Articles / prostate cancer

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men

Genetic factors can explain, at last in part, the higher incidence of prostate cancer among African American men compared with men of other ethnic groups. A team of scientists has identified MNX1 as a new oncogene – a gene than can cause cancer – that is more active in African American prostate cancer than in … Continue reading

‘Leaky calcium’ gene linked to sudden cardiac death in epilepsy
Articles / Neuroscience

‘Leaky calcium’ gene linked to sudden cardiac death in epilepsy

[See video below] Epilepsy is an extremely common disorder affecting people of all ages, from infants through teenagers to older adults. One of the most mysterious things about this disorder is that about 6 percent of the people with epilepsy have an unusually high incidence of sudden unexpected death. “Sudden unexpected death in epilepsy – … Continue reading