Image of the Month: Close and personal with bacteriophage P22
imaging / Nanotechnology

Image of the Month: Close and personal with bacteriophage P22

For nearly 30 years the laboratory of Dr. Wah Chiu, Distinguished Service Professor and Alvin Romansky Professor of Biochemistry and Molecular Biology at Baylor has been applying electron cryomicroscopy and computer reconstruction techniques to determine the 3-D structures of biological nanomachines, such as the P22 virus. This virus, a bacteriophage that infects Salmonella, has been … Continue reading

Image of the Month: Art meets science to show tomogram of neuron-like cell and model of bacterial virus
Articles / imaging / virus

Image of the Month: Art meets science to show tomogram of neuron-like cell and model of bacterial virus

Dr. Wah Chiu heads the lab of Electron Cryomicroscopy of Biological Nanomachines at Baylor College of Medicine. In Chiu’s lab, science not only resolves microscopic structures and relates them to their functional mechanisms, it also inspires artistic representations of those invisible worlds. The Chiu lab is dedicated to determine 3-dimensional structures of biological nanomachines by electron cryomicroscopy … Continue reading

DNA origami: designing structures with potential new uses in nanotechnology
algorithm / imaging / Nanotechnology

DNA origami: designing structures with potential new uses in nanotechnology

Scientists are using DNA to build nano-scaled devices – DNA origami – that could be used to improve our understanding of basic biological mechanisms as well as to design novel strategies to prevent or treat disease.   DNA is well known as the carrier of the genetic information in living organisms. The DNA double helix is flexible. … Continue reading

Image of the Month – Triple immunofluorescence of MCF-7 breast cancer cells.
Articles / Cancer / imaging

Image of the Month – Triple immunofluorescence of MCF-7 breast cancer cells.

IMAGE OF THE MONTH: MCF-7 breast cancer cells: Triple immunofluorescence for estrogen receptor (in red), androgen receptor (in green) and glucocorticoid receptor (in blue) demonstrates marked cellular heterogeneity. Image courtesy of Drs. Michael Mancini and Fabio Stossi of the Baylor College of Medicine Integrated Microscopy Core. Continue reading

Image of the Month: Mouse breast tumor cells
Articles / Cancer / imaging

Image of the Month: Mouse breast tumor cells

Mouse mammary carcinoma 4T1 cells in pseudo-colored scanning electron micrographs. These mouse breast tumor cells (shown in these pseudo-colored scanning electron micrograph, are used to create immunocompetent models of breast cancer with high rates of metastasis or spread. This is a laboratory models used to test new immune therapies against the disease and to study … Continue reading

Electronic algorithms help “find” patients lost in the system
algorithm / Articles / imaging / Patient safety / Process Improvement / Public Health

Electronic algorithms help “find” patients lost in the system

By Julia Parsons In an era when increasing pressures to increase clinical productivity can create data overload and when time is limited, sometimes the critical issue of telling patients about  an abnormal test can fall through the cracks. Researchers at Baylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center’s Center for Innovations in Quality, … Continue reading

Image of the Month — Graphene ribbon as an ideal scaffold.
Cancer / imaging

Image of the Month — Graphene ribbon as an ideal scaffold.

  The large surface area of graphene, a thin, tightly packed layer of carbon atoms, makes it an ideal scaffold to which you can attach a variety of bio-related materials such as drugs, and imaging contrast agents for imaging techniques such as MRI (magnetic resonance imaging)/computerized tomography (CT) etc. The conjugate can also enhance targeting  (via proteins/anti … Continue reading