A single species of gut bacteria can reverse autism-related social behavior in mice
Articles / behavior / diet / Microbiome / Prenatal

A single species of gut bacteria can reverse autism-related social behavior in mice

The absence of one specific species of gut bacteria causes social deficits in mice. Researchers at Baylor College of Medicine report June 16 in Cell that by adding this bacterial species back to the guts of affected mice, the researchers were able to reverse some of the mice’s behavioral deficits, which are reminiscent of symptoms … Continue reading

Twinning linked to genes tied to reproductive fitness traits
Articles / Genetics

Twinning linked to genes tied to reproductive fitness traits

Bearing fraternal twins, or dizygotic (DZ) twinning, runs in families, is potentially influenced by more than one gene and linked to a maternal factor. In a study published in the American Journal of Human Genetics, an international team reports the finding of two genes that are associated with increased odds for women bearing fraternal twins. … Continue reading

The mTOR pathway: a new avenue for breast cancer cells to promote tumor growth
Articles / Cancer / immunology

The mTOR pathway: a new avenue for breast cancer cells to promote tumor growth

Cancer cells respond in various ways to the body’s attempts to eliminate them. One strategy is to recruit immune cells in the body, such as the myeloid-derived suppressor cells (MDSCs), which are involved in the suppression of the body’s response against tumors. “There are alternative paths a tumor may take without the MDSCs, but those … Continue reading

Study found genes linked to happiness, depression and neuroticism
Articles / behavior / Genetics

Study found genes linked to happiness, depression and neuroticism

Ana María Rodríguez, Ph.D. In one of the largest studies on the genes involved in human behavior, a group of more than 190 researchers has analyzed genomic data from nearly 300,000 people and found genetic variants associated with our feelings of well-being, depression and neuroticism. The multi-institutional team, including a researcher from Baylor College of … Continue reading

New class of small molecule, SI-2, can drug the ‘undruggable’ steroid receptor coactivator-3
Articles / Cancer / drugs

New class of small molecule, SI-2, can drug the ‘undruggable’ steroid receptor coactivator-3

By Ana María Rodríguez, Ph.D. Steroid receptor coactivator-3, which is well-known for its role in cancer formation and proliferation, is usually considered ‘undruggable’ because this nuclear protein is large and unstructured. Attempts to block SRC-3 in cancer cells have resulted in the cells quickly adapting to this tactic by ramping up the production of the blocked … Continue reading

New insights from an autoimmunity-mediated atherosclerosis mouse model could pave the way to new therapies for cardiovascular diseases
Articles / autoimmunity / Heart Disease

New insights from an autoimmunity-mediated atherosclerosis mouse model could pave the way to new therapies for cardiovascular diseases

By Ana María Rodríguez, Ph.D. Patients with autoimmune disease have a higher risk of developing atherosclerosis and cardiovascular disease. Although studies have shown that human atherosclerotic plaques typically have antibodies against self-antigens, the role those complexes or immune cells play in the development of atherosclerotic lesions is still under investigation. To study how autoimmunity may lead … Continue reading

Discovery of the new hormone asprosin could have potential implications in treatment of diabetes
Articles / Diabetes / Endocrinology

Discovery of the new hormone asprosin could have potential implications in treatment of diabetes

By Dipali Pathak When Dr. Atul Chopra began studying a rare genetic condition called neonatal progeroid syndrome (NPS) he did not suspect that his discoveries could potentially affect the lives of millions of people living with a different condition, type 2 diabetes. The findings appear in the journal Cell. NPS keeps the body from accumulating fat, … Continue reading