A new era of norovirus research begins after succesfully growing the virus in the lab
Articles

A new era of norovirus research begins after succesfully growing the virus in the lab

Human noroviruses – the leading viral cause of acute diarrhea around the world – have been difficult to study because scientists had not found a way to grow them in the lab. Now, more than 40 years after Dr. Albert Kapikian identified human noroviruses as a cause of severe diarrhea, scientists at Baylor College of … Continue reading

Targeting two cell surface molecules can mitigate escape of solid glioblastoma tumors
Articles / Cancer / immunotherapy

Targeting two cell surface molecules can mitigate escape of solid glioblastoma tumors

One strategy to fight cancer cells involves ‘training’ the individual’s own immune system to fight the tumor, what is called immunotherapy. One form of immunotherapy involves ‘teaching’ the immune cells to recognize molecules on the cancer cell surface in ways that would lead to tumor destruction or better tumor control. Which cell surface molecules to … Continue reading

Primate study sheds light on human developmental disorders
Articles / Neuroscience

Primate study sheds light on human developmental disorders

We are now closer to better understanding brain disorders such as autism and schizophrenia. In a recent paper published in Nature, scientists have elucidated the genetic programs that guide the formation and development of specific regions within the brain of rhesus monkeys. Dr. Ed Lein, investigator at the Allen Institute for Brain Sciences in Seattle, … Continue reading

Altered metabolism in castration-resistant prostate cancer may point to new therapies
Articles / Cancer / metabolism

Altered metabolism in castration-resistant prostate cancer may point to new therapies

Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow. Although initially effective, this treatment often leads to the tumor becoming castration resistant — it is able to grow without androgen, a lethal condition. Researchers from Baylor College of Medicine and University of Michigan, along with collaborators in other … Continue reading

Narrowing down genes involved in male fertility
Articles / Fertility / Genetics

Narrowing down genes involved in male fertility

A couple’s fertility depends on both the female’s and male’s ability to reproduce, which relies on thousands of genes working properly. Around the world, infertility affects about 15 percent of couples and approximately 10 percent of men who are attempting to sire offspring. “Infertility is a serious condition and many of the genes responsible for … Continue reading

Researchers perform 3-D genome surgery on female’s silent X chromosome
Articles / Genetics / structural biology

Researchers perform 3-D genome surgery on female’s silent X chromosome

Females have two X chromosomes in each of their cells. Fully unfolded, each copy is two inches long. One of these two X chromosomes is inactive – its genes are turned off. This copy folds into a structure called the Barr body, a mysterious configuration that was discovered in 1949. Recently, scientists have shown that … Continue reading

Study identifies a new rare genetic syndrome associated with severe infections and lung disease in infants
Articles / Genetics / lungs

Study identifies a new rare genetic syndrome associated with severe infections and lung disease in infants

An international team of researchers has identified a new rare genetic condition – a chromosome breakage syndrome associated with severe infections and lung disease in infants. The discovery provides an explanation for this deadly pulmonary disease, possibilities to diagnose it and opportunities for developing alternate ways to treat it. The results appear July 18 in … Continue reading