Analyzing cryo-electron tomography images just got faster
Articles / Cryo-electron tomography

Analyzing cryo-electron tomography images just got faster

To visualize macromolecules frozen in action and details of structures inside of cells researchers use cryo-electron tomography. This method provides 100 times better resolution than the best light microscope; this information cannot be obtained by any other current method. “However, the need for about one man-week of effort to manually annotate all of the 3-D … Continue reading

How estrogen regulates gene expression
Articles / Endocrinology / estrogen

How estrogen regulates gene expression

Estrogens are a group of hormones that are essential for normal female sexual development and for the healthy functioning of the reproductive system. They also are involved in certain conditions, such as breast cancer. Estrogen also plays a role in male sexual function. These hormones carry out their functions by turning genes on and off … Continue reading

This two-step approach can expedite finding answers to complex genetic conditions
Articles / neurodevelopmental disorders

This two-step approach can expedite finding answers to complex genetic conditions

To function normally, the human brain requires the right amount of a number of proteins, including MeCP2. Having twice the normal amount of MeCP2, the result of having an extra copy of the gene MECP2, causes severe neurological disorders that include intellectual disability, autism spectrum disorders, motor dysfunction and other medical complications. “Animal models that … Continue reading

More than an anticoagulant; heparin also promotes appetite in mice
appetite control / Articles

More than an anticoagulant; heparin also promotes appetite in mice

Naturally-produced heparin is well-known for its role as an anticoagulant. Heparin is also widely used as a medication to prevent blood clotting. “In addition to its role as an anticoagulant, naturally-produced heparin has been known to affect other biological functions. In this study, we are among the first groups to investigated heparin’s potential role in … Continue reading

Device that induces a mild localized ‘fever’ could treat vascular involvement in cancer
Articles / Innovation in cancer treatment

Device that induces a mild localized ‘fever’ could treat vascular involvement in cancer

The prognosis of a cancer patient relies significantly on the ability of the surgeon to remove all the tumor, including a cancer-free boundary, leaving what surgeons call a tissue margin negative for cancer cells. But this is not always possible. Leaving tumor tissue behind reduces the patient’s chance for recovery because the unremoved tumor may … Continue reading