Bacteria and mitochondria have a common language
Articles / Microbiome

Bacteria and mitochondria have a common language

It’s not news that microbes can alter the physiology of the organisms in which they live, but the actual molecular mechanisms that mediate their interactions have been largely unknown. Understanding how microbes and their hosts influence each other’s functions is one of the interests of Dr. Meng Wang. “Microbes living inside another organism, the host, … Continue reading

‘Silent seizures’ discovered in patients with Alzheimer’s disease
Alzheimer's disease / seizures

‘Silent seizures’ discovered in patients with Alzheimer’s disease

Deep in the brains of two patients with Alzheimer’s disease, the main memory structure, the hippocampus, displays episodic seizure-like electrical activity. These nonconvulsive hippocampal seizures are the first signs of ‘silent’ brain electrical network dysfunction described in patients with Alzheimer’s disease, a condition affecting more than 5 million people in the U.S. “About 10 years … Continue reading

‘MARRVEL’: a new way to compile big data in a human-centric way
Articles / Gene variants database search

‘MARRVEL’: a new way to compile big data in a human-centric way

When a group of researchers in the Undiagnosed Disease Network at Baylor College of Medicine realized they were spending days combing through databases searching for information regarding gene variants, they decided to do something about it. They created MARRVEL (Model organism Aggregated Resources for Rare Variant ExpLoration) to help not only their own lab but … Continue reading