Image of the Month: Artist’s rendition of antigen recognition
Articles

Image of the Month: Artist’s rendition of antigen recognition

In organ transplantation the main target of the immune response is the major histocompatibility complex (MHC) which is expressed on the surface of donor cells. During an allograft transplant, donor MHC antigens are recognized by the graft recipient’s immune system triggering an immune response. Histocompatibility testing of donor and recipient tissues for MHC antigens can … Continue reading

Two Baylor College of Medicine faculty members named to the National Academy of Medicine
Articles / Honors

Two Baylor College of Medicine faculty members named to the National Academy of Medicine

Dr. Malcolm Brenner, founding director of the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist Hospital, and Dr. Cheryl Walker, founding director of the Center for Precision Environmental Health at Baylor, both renowned leaders in their respective fields, were elected to membership in the National Academy … Continue reading

$27.9 million from NIH to support Baylor’s Knockout Mouse Project
Articles / Award / Genetics

$27.9 million from NIH to support Baylor’s Knockout Mouse Project

Nearly $28 million has been awarded to Baylor College of Medicine’s Knockout Mouse Project led by Dr. Arthur Beaudet, professor of molecular and human genetics, and Dr. Mary Dickinson, professor of molecular physiology and biophysics. The grant, to be used over 5 years, was awarded by the National Institutes of Health as a renewal of … Continue reading

Variations in gene ATAD3A can result in distinct neurological syndromes
Articles / Human genetics

Variations in gene ATAD3A can result in distinct neurological syndromes

Research has revealed that a group of rare neurological syndromes for which there was no cause can be the result of variations in the gene ATAD3A. The study, which appears in The American Journal of Human Genetics, shows that certain human variants of ATAD3A are associated with a lower number of mitochondria while the gene equivalents in the fruit … Continue reading

A new mechanism to explain benign prostatic hyperplasia
Articles / inflammation / prostate

A new mechanism to explain benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate, affects about half the men between 51 and 60 years of age, and nine out of 10 men older than 80. How BPH happens, however, is still open for debate. “Scientists have considered that inflammation can cause BPH. But how inflammation initiates in human prostate … Continue reading