Mutations in RERE gene result in features that coincide with those associated with 1p36 deletion syndrome
Articles / Genetics

Mutations in RERE gene result in features that coincide with those associated with 1p36 deletion syndrome

By Ana María Rodríguez, Ph.D. Missing the tip of chromosome 1, a region called 1p36, is a relatively common cause of intellectual disability affecting one in 5,000 babies. These children may also have delayed development, seizures, heart and kidney defects, and problems with vision and hearing. The number and severity of these medical conditions varies greatly … Continue reading

Profile feature: Dr. Adam Kuspa
Interview

Profile feature: Dr. Adam Kuspa

The following insideview interview appeared in Nature Outlook Supplement on Research Commercialization, May 5, 2016. Baylor College of Medicine (BCM) has built a reputation as a great basic science research institution, spending over $400 million on research annually. However, in the past, the college’s commercialization results lagged behind its strength as a research powerhouse. The development … Continue reading

Crystal structure of PKGI suggests a new activation mechanism
Articles / Biochemistry / Heart Disease / structural biology

Crystal structure of PKGI suggests a new activation mechanism

By Ana María Rodríguez, Ph.D. Kinases form a large family of proteins that seem to be involved in nearly every aspect of cell life. Faulty protein kinases have been found in a number of human conditions, including cardiovascular diseases, cancer and diabetes, and this has triggered much interest in understanding their regulatory mechanisms in order … Continue reading

Born to run? Study suggests love of exercise starts in the womb
Articles / Prenatal

Born to run? Study suggests love of exercise starts in the womb

By Ana María Rodríguez, Ph.D. When pregnant female mice exercise their offspring receive an unexpected benefit; they tend to be more physically active than mice born to mothers that did not exercise during pregnancy. The research appears in The FASEB Journal. Dr. Robert A. Waterland, associate professor of pediatrics – nutrition and of molecular and … Continue reading