Neonatal dose of estrogen may prevent catastrophic epilepsy
Articles

Neonatal dose of estrogen may prevent catastrophic epilepsy

By Ruth SoRelle, M.P.H. Some children are born with a devastating form of childhood epilepsy called infantile spasms that cause a life of severe seizures and lifelong disability. In a study that appears in the journal Science Translational Medicine, Dr. Jeffrey Noebels, professor of neurology, neuroscience and molecular and human genetics at Baylor College of Medicine, … Continue reading

Opinion: What Women Need to Succeed in Science Attracting females to research careers—and keeping them there
Articles

Opinion: What Women Need to Succeed in Science Attracting females to research careers—and keeping them there

By Huda Y. Zoghbi and Paul Greengard.  Nearly every discussion of women in the sciences eventually arrives at the same question: Why, at a time when women are leading countries and multibillion-dollar corporations and are as likely as men to major in science as undergraduates, do we still see so few women pursuing leadership positions … Continue reading

Study points way to potential new treatment for brittle bone disease
Articles

Study points way to potential new treatment for brittle bone disease

By Ruth SoRelle, M.P.H.  Patients with osteogenesis imperfecta (brittle bone disease) treated with teriparatide, a form of parathyroid hormone approved for treatment of women with osteoporosis, had stronger bones in the lower spine and the hip when compared to a group of similar patients who received placebo or an inactive medicine, said researchers from three academic institutions – … Continue reading

High throughput microscopy zeroes in on new estrogen receptor regulator
Cancer / Microscopy

High throughput microscopy zeroes in on new estrogen receptor regulator

A high throughput microscopy technique enabled Baylor College of Medicine  researchers to identify a new modulator of estrogen receptor alpha that they called UBR5. It is a highly amplified gene in many tumors, including breast, prostate and ovarian cancer. With high throughput microscopy and automated image analysis, researchers can evaluate many mechanistic measures under several hundred … Continue reading